This chapter explores the influence of liquid temperature on sonochemical processes, focusing on the behavior of single bubbles during ultrasonic irradiation. It examines the impact of temperature on bubble dynamics, chemical reactions, and the generation of radicals and reactive species using both simplified adiabatic models and more advanced approaches. Key factors such as gas solubility, viscosity, and vapor pressure are discussed to understand their role in sonochemical efficiency. The experimental findings reveal the complex and often contradictory effects of temperature, which depend on experimental conditions, solute properties, and sonochemical setup. The theoretical calculations highlight the complexity, suggesting optimal conditions that vary with operational parameters. By combining theoretical models and experimental observations, the chapter provides a comprehensive understanding of how liquid temperature affects sonochemical processes.