Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics, in order to entail a rich dynamical repertoire and optimize functional capabilities, should operate at the brink of a phase transition, i.e., at the edge between different collective phases. In recent years, research guided by the advent of high-throughput data and new theoretical developments has contributed to making a quantitative validation of such a hypothesis. Here we review recent advances in this field, stressing our contributions. In particular, we use data from thousands of individually recorded neurons in the mouse brain and tools such as a phenomenological renormalization group analysis, theory of disordered systems, and random matrix theory. These combined approaches provide strong evidence of quasi-universal scaling and near-critical behavior emerging in different brain regions. Moreover, we design artificial neural networks under the reservoir-computing paradigm and show that their internal dynamical states become near critical when we tune the networks for optimal performance. These results not only open new perspectives for understanding the ultimate principles guiding brain function but also towards the development of brain-inspired, neuromorphic computation.

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Unveiling the Intrinsic Dynamics of Biological and Artificial Neural Networks: From Criticality to Optimal Representations

  • Guillermo B. Morales,
  • Serena di Santo,
  • Miguel A. Muñoz

摘要

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics, in order to entail a rich dynamical repertoire and optimize functional capabilities, should operate at the brink of a phase transition, i.e., at the edge between different collective phases. In recent years, research guided by the advent of high-throughput data and new theoretical developments has contributed to making a quantitative validation of such a hypothesis. Here we review recent advances in this field, stressing our contributions. In particular, we use data from thousands of individually recorded neurons in the mouse brain and tools such as a phenomenological renormalization group analysis, theory of disordered systems, and random matrix theory. These combined approaches provide strong evidence of quasi-universal scaling and near-critical behavior emerging in different brain regions. Moreover, we design artificial neural networks under the reservoir-computing paradigm and show that their internal dynamical states become near critical when we tune the networks for optimal performance. These results not only open new perspectives for understanding the ultimate principles guiding brain function but also towards the development of brain-inspired, neuromorphic computation.