The learning factory model has been demonstrated to be an effective framework for the integration of the education, industry, and government sectors. This research study describes the Center for the Future of Mobility, which is focused on sustainability and innovative solutions to enhance urban transportation in Mexican cities. The center’s approach integrates research, innovation, collaboration, and the development of advanced electromobility technologies, offering an immersive learning environment that facilitates the integration of didactic processes. This enables the formation of strategic alliances between industry, government, and academia for the purpose of developing competencies in sustainable mobility. The main contribution of this study is to present a working model and the open innovation ecosystem used in Tecnológico de Monterrey. These could serve as a base model for scaling up into a learning factory dedicated to industry-partnered, active learning. Furthermore, this study presents the future clean mobility district challenge as an example that features a collaborative network of supporting industrial partners with the university, and academic opportunities for the improvement of competencies. This involves the pedagogic design of the challenge, the methodology, and the socio-technical ecosystem development. Finally, a discussion on the findings and learnings of the model and challenge implementation.