In this chapter, the systemic nature of digital transformation of human labor and the impact of data-based systems (DS) on human work is addressed, namely, the end of the strive of the economy for full employment. This ethical analysis takes this systemic changeover seriously by avoiding placing the burden of it on the shoulders of individuals—calling irresponsibly for in-service training and upskilling for a job-market that won’t exist anymore—but by developing a systemic response to a systemic transformation. A decoupling of income from work is considered a possible reaction to the massive reduction of paid professional tasks for humans in order to guarantee survival and a life as a human with human dignity for all humans.