This chapter offers comments on how this psychiatric and neurological approach to religion relates to sociological discussions of religious origins offered by Emile Durkheim, and then does the same to Max Weber’s discussion of religiously based charisma. Specifically, it suggests that Durkheim’s discussion of the origins of religion within collective celebrations glosses over the importance of shamanic psychical experiences, and it also shows that two probable epileptics and one likely narcissist are embedded in Weber’s identification and development of the charismatic term. Moreover, the different interpretations about sex that Weber identified between St. Paul and Muhammad may be related responses to epileptic seizure activity.