Women empowerment has emerged as a dynamic force for shaping policy decisions across developing nations, particularly in India. In recent years, promoting empowerment through entrepreneurship has become a key strategy to harness the potential of the female workforce. This study explores the various factors that can facilitate the empowerment of tribal women in North-east India by encouraging their participation in agricultural and allied entrepreneurial activities. The study conducts primary survey of 360 tribal women who are engaged in backyard farming and animal husbandry related activities. Structural equation modelling is applied to accesses the role of agricultural entrepreneurship. The study finds that entrepreneurship does result in economic empowerment of tribal women which indeed acts as a catalyst for sustainable development. The study underscores the importance of targeted policies and development programmes to advance Sustainable Development Goal 5, particularly in eliminating gender-based discrimination and enhancing women’s participation in economic, social, and political decision-making.