Virtual Reality (VR) technology holds great promise in revolutionizing offline CBRN (Chemical, Biological, Radiological, and Nuclear) training. This research explores the potential of Immersive CBRN training through VR with a primary focus on first responders’ insights. First, it assesses the current state of CBRN training, highlighting its strengths and weaknesses. Then, it delves into a survey of first responders, uncovering their needs and expectations regarding VR integration. This includes examining the importance of user-friendly interfaces (HCI), the potential for VR to simulate emotions for enhanced psychological realism, and the role of Artificial Intelligence (AI) in assessing performance and dynamically generating training scenarios. This paper uses survey results and other studies to show how VR can be very useful for training in situations involving CBRN threats. It connects technology with what’s actually needed in the real world. Ultimately, it underscores the transformative power of VR technology in making CBRN training safer, immersive and effective, shaping a future of enhanced preparedness.