Transcatheter Coarctoplasty and Isolated Interrupted Aortic Arch Treatment in Adults
摘要
CoA is a congenital heart defect that results in an obstruction of blood flow through the aorta. This condition is characterized by a narrowed segment of the aorta, which features localized thickening of the medial layer, accompanied by some infolding of the media and the presence of neo-intimal tissue. BAV is frequently associated with CoA, occurring in over half of CoA patients, and can lead to AI, AS, or aortic dilation and dissection. Additionally, intracranial aneurysms may develop in 2%–10% of cases. In adults, the most common initial symptom is systemic hypertensionSystemic hypertension, which is often discovered incidentally. The leading causes of death associated with CoA include congestive heart failure, aortic dissectionAortic dissection and rupture, endocarditis, premature coronary artery disease, and intracranial hemorrhage. For neonates and adolescents, the preferred treatment is surgical intervention, although there is a risk of recoarctationRecoarctation and aneurysm formation. In adult patients, the more suitable treatment for those indicated for coarctoplasty is a transcatheter approach, with the primary goal being stenting.