Scholarlink

Magnetic hyperthermiaMagnetic hyperthermia has emerged as a promising cancer treatmentCancer treatment strategy wherein magnetic nanoparticlesMagnetic nanoparticles (MNPs) are employed to generate localized heat under the influence of an alternating magnetic fieldAlternative magnetic field (AMF). These nanoparticles are responsible for inducing cell death selectively at the tumor site without affecting healthy cells. This chapter explores various modifications of magnetic nanoparticlesMagnetic nanoparticles in inducing hyperthermiaHyperthermia, including their combination with chemotherapy and radiotherapyRadiotherapy, to enhance therapeutic efficacy. Special emphasis is placed on surface functionalizationSurface functionalization strategies, such as coating of polymerPolymers/biopolymers, silica, graphene oxideGraphene oxide, and dendrimersDendrimers; ligand exchangeLigand exchange; surfactant modifications; and host–guest complexation, which improve biocompatibilityBiocompatibility, targeting efficiency, and drug-loading capacity of the nanostructuresNanostructures. Additionally, the role of iron oxide-based MNPs in ferroptosisFerroptosis, an emerging cancer cell death pathway, is discussed. While magnetic nanocarriersMagnetic nanocarriers offer immense potential in targeted drug deliveryTargeted drug delivery, various challenges such as toxicityToxicity, stability, target specificity, biocompatibilityBiocompatibility, and controlled drug release remain key hurdles for clinical translation. Addressing these issues through innovative nanomaterialNanomaterials engineering will pave the way for more effective and safer cancer therapiesCancer therapy.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Magnetic Hyperthermia Using Magnetic Nanoparticles: A Promising Strategy in Cancer Treatment

  • 章节

  • 发表日期：

    2025年

查看全文
  • Shefali Shukla,
  • Sreya Jayan,
  • P. K. Hasna,
  • Shikha Gulati

摘要

Magnetic hyperthermiaMagnetic hyperthermia has emerged as a promising cancer treatmentCancer treatment strategy wherein magnetic nanoparticlesMagnetic nanoparticles (MNPs) are employed to generate localized heat under the influence of an alternating magnetic fieldAlternative magnetic field (AMF). These nanoparticles are responsible for inducing cell death selectively at the tumor site without affecting healthy cells. This chapter explores various modifications of magnetic nanoparticlesMagnetic nanoparticles in inducing hyperthermiaHyperthermia, including their combination with chemotherapy and radiotherapyRadiotherapy, to enhance therapeutic efficacy. Special emphasis is placed on surface functionalizationSurface functionalization strategies, such as coating of polymerPolymers/biopolymers, silica, graphene oxideGraphene oxide, and dendrimersDendrimers; ligand exchangeLigand exchange; surfactant modifications; and host–guest complexation, which improve biocompatibilityBiocompatibility, targeting efficiency, and drug-loading capacity of the nanostructuresNanostructures. Additionally, the role of iron oxide-based MNPs in ferroptosisFerroptosis, an emerging cancer cell death pathway, is discussed. While magnetic nanocarriersMagnetic nanocarriers offer immense potential in targeted drug deliveryTargeted drug delivery, various challenges such as toxicityToxicity, stability, target specificity, biocompatibilityBiocompatibility, and controlled drug release remain key hurdles for clinical translation. Addressing these issues through innovative nanomaterialNanomaterials engineering will pave the way for more effective and safer cancer therapiesCancer therapy.