Minimally invasive, image-guided, percutaneous decompression techniques yield significant and long-lasting results upon pain reduction and mobility improvement in symptomatic patients with disk herniation. These decompression techniques include a variety of mechanical, thermal, or chemical instruments/agents used to extract/destroy a part of the nucleus pulposus, resulting in a significant intradiscal pressure decrease (as stated in the Hijikata theory), allowing the herniated part to collapse inwards. These techniques are considered either first-line therapies or attractive alternatives to surgical treatments due to their high success (~85%) and low complication rates (<0.5%).