Hand impairments caused by conditions such as strokes and radial nerve palsy significantly impact the quality of life for many individuals, particularly in developing regions with limited access to rehabilitation services. Accurate measurement of the range of motion (ROM) of the hand is crucial for effective therapy and recovery monitoring. Traditional methods using goniometers are often cumbersome and dependent on the patient’s ability to maintain static positions. This study utilizes a low-cost flexible sensor glove designed to measure the minimum range of ROM required to perform activities of daily living (ADLs). The prototype, developed using readily available flex sensors, was tested on 40 participants performing 11 ADLs. The investigation resulted in a ROM of \(39.88^\circ \) – \(69.42^\circ \) , \(18.92^\circ \) – \(78.1^\circ \) , and \(13.42^\circ \) – \(60.15^\circ \) for the metacarpophalangeal (MCP), proximal interphalangeal (PIP) and interphalangeal joints (IP), respectively. These ranges indicate the necessary ROM for an individual to maintain functional independence based on the chosen ADLs. While the glove measurements were compared to those in previous studies, variations in measurement techniques, participant numbers and the selected ADLs influenced the variations observed in the results.