American Indian/Alaska Native people represent resilient nations throughout the United States. However, a history of continuing oppression and genocidal systems have caused high rates of substance use disorders and mental health issues (O Keefe et al., 2021). The absence of resources in mental health care and various barriers to assistance continue these inequalities. Psychologists attempted to tackle these problems by introducing Western evidence-based strategies that failed to recognize Indigenous values, and over time, it became clear that these Western practices did not work (O’Keefe et al., 2021). However, incorporating Indigenous ways of knowing and Western mental health support may produce an ideal structure in which Indigenous people may be more open to receiving mental health services, thus restoring balance and overall wellness and supporting healing traditions. A culturally responsive methodology called the Sweetgrass Method (SGM) is a community-based participatory practice approach incorporating practice-based evidence (PBE). The SGM addresses the cultural differences in how clients view illness and healthcare by engaging family and tribal community members in addiction treatment (Baez et al., Sweetgrass Method: A culturally responsive approach to mental health. Journal of Indigenous Research, 2022). When practitioners use the SGM, a healthy dialogue with AI/AN clients can begin by incorporating culturally responsive introspection, communication, and the continuation of culturally responsive services tailored for the client.