When aircraft operate in desert environments, solid particle erosion can accelerate the failure of critical components such as compressor blades in aero-engines, thereby jeopardizing aviation safety. In this study, the experiment and simulation of solid particle erosion on the surface of titanium alloy (TC4) were conducted. Solid particle erosion experiments were conducted using an RTEC-AJ1000 airflow sandblast tester, establishing the relationships between the mass loss and volume loss of TC4 alloy and erosion duration. Furthermore, the surface morphology of TC4 alloy was observed via scanning electron microscopy (SEM), revealing the material removal mechanisms such as microcrack formation, lip-edge detachment, plastic deformation, and delamination. In addition solid particle erosion simulation was conducted based on Oka erosion model. The simulated erosion mass loss results for TC4 specimens closely matched experimental data across various erosion durations. The deviation between simulated and experimental results increased with erosion time, likely attributable to surface hardening effects caused by prolonged erosion exposure.