German reunification and the end of the Cold War heralded a new era in international relations in general and in the German-American relationship in particular. Against this backdrop, this chapter examines both general trends and pivotal episodes in U.S. foreign policy—especially in German-American relations—during the Clinton years (1993–2001), a period during which the United States occupied a historically unrivaled position. After the demise of the Soviet Union, policy-makers in Washington viewed Europe and the world from a position of military preeminence, economic promise, and cultural supremacy unmatched in recorded history. William J. Clinton, the newly elected president faced with this unprecedented reality, entered the White House with a primary focus on the economy. In foreign policy, the doctrine of “democratic enlargement” replaced the long-standing “containment” strategy of the Cold War, shifting U.S. strategy toward the global spread of democracy and the expansion of free trade and free markets. Overall, the chapter argues, U.S. soft power toward Germany remained strong throughout the Clinton years. Given the seismic shifts in global politics during the early 1990s, this was far from certain. Germans remained widely attracted to the United States—its culture, values, policies, and, not least, its leading political figures. Especially at the leader-to-leader level, the personality factor played a highly consequential role. By and large, the Clinton years thus marked a period of mutual friendship between Germany and the United States. Nevertheless, growing transatlantic tensions toward the end of Clinton’s tenure regarding key soft power indicators—most notably multilateralism—foreshadowed the more troubled times that lay ahead.