Infertility is a prevalent condition in the United States that disproportionately affects women of color. Unfortunately, women of color experience worse outcomes from fertility treatment as well, but the root causes of these disparities remain insufficiently understood. Infertility and its treatments may lead to stress which, when chronic, can negatively impact quality of life. Being a person of color can amplify the intensity of stress experienced. This burden of stress is often intensified for people of color, contributing to higher treatment discontinuation rates among women of color—even when financial obstacles are removed. Furthermore, stress has been shown to negatively influence pregnancy and delivery outcomes, potentially compounding existing health inequities. Addressing these challenges will require thoughtful, targeted interventions aimed at both reducing stress and narrowing fertility outcome disparities. With concerted effort, there is hope that such measures will bring about more equitable reproductive health experiences for all.