This chapter introduces how the organizational context in terms of structural characteristics can contribute to sustainable employment for PWD. The chapter starts by examining the dynamics of inclusion in the public, private, and third sectors, focusing on sector-specific variations that can affect sustainable employment. Next follows an examination of how low-skill and high-skill industries can impact sustainable employment for PWD. The chapter also sheds light on how small firm informality on the one hand and large firm formality on the other, are associated with different challenges and opportunities when employing PWD. The theoretical predictions are followed by empirical evidence on the associations between structural characteristics and sustainable employment for PWD. Next, the chapter links sustainable employment with configurations of structural characteristics—combinations of sector, industry, and size—with examples of how the interplay of various challenges related to specific structural traits can be tackled strategically by managers. The chapter concludes by highlighting the importance of using the evidence-based knowledge of structural characteristics to develop effective, context-specific inclusion practices and strategies for managers and organizations committed to creating sustainable employment for PWD.