Complexity theory has the potential to be an inspiring and invigorating contribution to the study of integrated care. In this chapter, I propose that using Preiser’s six organizing principles of a CAS provides a general typology around which we can design, evaluate, and research integrated care interventions to develop a deeper, richer understanding of integrated care systems and interventions. We have already acknowledged that integrated care is complex and surely that behoves us to embrace complexity theory like many other disciplines have to unpack the black box of integrated care.