Dyslexia is a common reading disorder, often characterized by slow or inaccurate word recognition. Inappropriate typography design may pose an additional challenge for struggling readers, particularly when visual impairments contribute to their difficulties. One crucial aspect of typography is the choice of typeface. Previous studies examining dyslexia-friendly typefaces in Latin and Cyrillic scripts yielded inconclusive results, with participants’ visual skills remaining unassessed. This study aimed to address this gap by recruiting adolescents in Grades 8–11 exhibiting signs of visual and nonvisual dyslexia. We tested three typefaces in Russian: the dyslexia-friendly LexiaD, the default font for Google applications, Roboto, and the widely used Times New Roman found in textbooks. This was done in a lexical decision task that primarily reflects the speed of word recognition. Participants were tasked with identifying, via key presses, whether presented letter strings were real Russian words or pseudowords, with their reaction times measured. The findings showed that in the nonvisual subgroup words in LexiaD were recognized slower than in Roboto and Times New Roman, the difference between control fonts were insignificant. However, adolescents with visual dyslexia showed no significant difference between Times New Roman and LexiaD, with Roboto being identified as the most effective font. These results suggest that inclusive typography features should be tested, taking into account dyslexia subtypes. We do not recommend using Times New Roman in digital texts for struggling readers in Russian; instead, Roboto may be a better option.