Conductive biomaterials integrated into additive manufacturing processes have emerged as promising avenues for developing innovative products with enhanced functionalities. This chapter provides a comprehensive overview of the design, fabrication, and application of conductive biomaterial-based additive manufactured products for wound healing and skin tissue engineering. The chapter begins with an introduction to the challenges associated with conventional wound healing methods and the growing demand for novel approaches to address these challenges. The following section explores the fundamentals of additive manufacturing, highlighting its adaptability and appropriateness for the fabrication of complicated structures with exact control over the design and composition of materials. A notable comprehensive analysis of the properties and functions of conductive biomaterials, emphasizing their distinct electrical, mechanical, and biological traits that make them suitable for tissue engineering applications, has been discussed. The incorporation of conductive biomaterials, such as graphene, carbon nanotubes, and conductive polymers, among others into additive manufacturing processes enables the development of scaffolds and dressings with enhanced conductivity, which can modulate cellular behaviour and promote tissue regeneration. Furthermore, the chapter explores various strategies for optimizing the fabrication process to ensure the biocompatibility, mechanical integrity, and electrical conductivity of the resulting products. It also examines the influence of scaffold architecture, surface topography, and electrical stimulation parameters on cell proliferation, differentiation, and tissue regeneration. Taken together, this chapter underscores the potential of conductive biomaterial-based additive manufactured products as innovative solutions for addressing the unmet needs in wound healing and skin tissue engineering. It highlights the significance of materials science, and biomedical engineering, working together to progress this fascinating area and put research results into clinical practice.

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Conductive Biomaterials-Based Additive Manufactured Products for Wound Healing and Skin Tissue Engineering

  • Sony Priyanka Bandi,
  • Bahareh Alizadeh,
  • Shreya Shashank Chauhan,
  • Deepanjan Datta

摘要

Conductive biomaterials integrated into additive manufacturing processes have emerged as promising avenues for developing innovative products with enhanced functionalities. This chapter provides a comprehensive overview of the design, fabrication, and application of conductive biomaterial-based additive manufactured products for wound healing and skin tissue engineering. The chapter begins with an introduction to the challenges associated with conventional wound healing methods and the growing demand for novel approaches to address these challenges. The following section explores the fundamentals of additive manufacturing, highlighting its adaptability and appropriateness for the fabrication of complicated structures with exact control over the design and composition of materials. A notable comprehensive analysis of the properties and functions of conductive biomaterials, emphasizing their distinct electrical, mechanical, and biological traits that make them suitable for tissue engineering applications, has been discussed. The incorporation of conductive biomaterials, such as graphene, carbon nanotubes, and conductive polymers, among others into additive manufacturing processes enables the development of scaffolds and dressings with enhanced conductivity, which can modulate cellular behaviour and promote tissue regeneration. Furthermore, the chapter explores various strategies for optimizing the fabrication process to ensure the biocompatibility, mechanical integrity, and electrical conductivity of the resulting products. It also examines the influence of scaffold architecture, surface topography, and electrical stimulation parameters on cell proliferation, differentiation, and tissue regeneration. Taken together, this chapter underscores the potential of conductive biomaterial-based additive manufactured products as innovative solutions for addressing the unmet needs in wound healing and skin tissue engineering. It highlights the significance of materials science, and biomedical engineering, working together to progress this fascinating area and put research results into clinical practice.