A novel approach to managing otolaryngology involves using additive manufacturing techniques with biomaterials to produce customized bioengineered items. The medical specialty of otolaryngology, which treats conditions affecting the ear, nose, and throat, frequently needs to provide patients with exact and customized therapy. The specific anatomical variances and needs of each patient may not be adequately addressed by traditional approaches. This novel technology provides new levels of customization and precision by utilizing modern biomaterials and additive manufacturing, also referred to as 3D printing. A patient’s anatomy and pathology can be considered when creating custom implants, prosthetics, and other devices thanks to the integration of patient-specific data, such as medical imaging. Additionally, the danger of rejection or problems is reduced since biomaterials chosen for their biocompatibility and biomechanical qualities guarantee appropriate integration andj functionality within the patient’s body. This new era in otolaryngology, where personalized solutions can result in better patient outcomes, shorter surgical times, and higher quality of life, is heralded by the synergistic combination of biology and technology. In the realm of otolaryngology, the chapter lays the groundwork for future research and development of biomaterials-based additive manufacturing, offering promising developments in patient care and treatment methods.