This chapter identifies evidence-based interventions and policy implementation strategies, and disparities in promoting sexual and reproductive health and rights (SRHR) and increasing penalties for gender-based violence (GBV). The Caribbean has made significant progress in several areas, including the development of policies to improve universal access to high-quality sexual and reproductive health information and services, laws to strengthen survivor protection, a broadening of the categories of individuals protected from GBV, and increased penalties for GBV perpetrators. Furthermore, advancements have been made in several SRHR priority areas, such as adolescent fertility rates, child marriage, and the use of contraceptives, in countries across Africa, particularly in Sub-Saharan Africa. Some crucial concerns are the foundation of the advancement. A large body of research in the field of SRHR explains the nature and consequences of women’s poor health and economic outcomes, as well as barriers to access. Although there has been improvement in legislation and policy throughout the Caribbean, most countries’ implementation of these changes has been equitably limited and insufficient to guarantee that individuals have access to the necessary information and services. Where progress exists, it is not evenly distributed across the various population categories. Further research on evidence-based interventions and policies to improve the situation of women and girls in Sub-Saharan Africa is necessary. The chapter reveals that progress in health and social outcomes is constantly impeded due to poor implementation of interventions and policies equitably, thereby demanding an understanding of an inclusive strategy that addresses critical components of SRHR and GBV implementation.