Scholarlink

Rheumatoid arthritis (RA) is a chronic, autoimmune, and inflammatory systemic disease that mainly involves diarthrodial joints, with cartilage degradation, bone erosion, and progressive loss of articular function. The cross-talk between central nervous, endocrine, and immune networks is named neuroendocrine immune (NEI) system and is highly perturbated in course of RA and other immune-mediated diseases. The restoration of normal functionality of NEI system, by following physiological circadian and circannual rhythms, is crucial for the optimal treatment of this complex disease.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Rheumatoid Arthritis

  • 章节

  • 发表日期：

    2026年

查看全文
  • Emanuele Gotelli,
  • Stefano Soldano,
  • Vanessa Smith,
  • Maurizio Cutolo

摘要

Rheumatoid arthritis (RA) is a chronic, autoimmune, and inflammatory systemic disease that mainly involves diarthrodial joints, with cartilage degradation, bone erosion, and progressive loss of articular function. The cross-talk between central nervous, endocrine, and immune networks is named neuroendocrine immune (NEI) system and is highly perturbated in course of RA and other immune-mediated diseases. The restoration of normal functionality of NEI system, by following physiological circadian and circannual rhythms, is crucial for the optimal treatment of this complex disease.