The growing ageing population in Europe has led to a significant increase in the demand for caregiving services for older adults and individuals with physical or cognitive impairments. In a context where caregiving remains a family responsibility, especially for women, it is essential to take into consideration caregivers’ needs and well-being. In this study, relying on 2019 European Health Interview Survey (EHIS) data, we address the relationship between providing informal caregiving – to both family and non-family members – and the caregiver’s mental health in 29 European countries, from a gender perspective. Preliminary results show the existence of a significant negative relationship between caregiving responsibilities and mental health, at least in terms of feeling down, depressed or hopeless. In addition, this relationship seems to change depending on individual characteristics – sex, primarily – and the caregiver- recipient relationship. In the following steps, we will deepen possible heterogeneous effects, also considering the intensity of the caregiving activities.