Scholarlink

Proton (1H) magnetic resonance spectroscopy (MRS) has shown great promise to detect and longitudinally monitor early pathological changes across the Alzheimer’s disease (AD) spectrum, highlighting its potential in early diagnosis through noninvasive assessment of neurochemical alterations. The application of 1H MRS in evaluating several metabolites offers insights into the biochemical changes in the preclinical, prodromal, and dementia stages of AD, underscoring its value in understanding disease pathophysiology and aiding in the development of preventative therapies.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Application of Proton MRS in the Alzheimer’s Disease Continuum: Recent Advances and Future Directions

  • 章节

  • 发表日期：

    2025年

查看全文
  • Firat Kara,
  • Kejal Kantarci

摘要

Proton (1H) magnetic resonance spectroscopy (MRS) has shown great promise to detect and longitudinally monitor early pathological changes across the Alzheimer’s disease (AD) spectrum, highlighting its potential in early diagnosis through noninvasive assessment of neurochemical alterations. The application of 1H MRS in evaluating several metabolites offers insights into the biochemical changes in the preclinical, prodromal, and dementia stages of AD, underscoring its value in understanding disease pathophysiology and aiding in the development of preventative therapies.