In response to the increasing need for secure and efficient management of prescription drugs, particularly controlled substances like opioids and sedatives, this paper proposes a biometric medication storage system. The system leverages fingerprint and facial recognition technologies to provide stringent access control, ensuring that only authorized personnel can access sensitive medications. Unlike traditional security methods, biometric systems offer higher security levels as biometric traits are unique, difficult to forge, and cannot be easily lost or forgotten. The integration of these technologies enhances not only security but also operational efficiency, reducing authentication time and simplifying access in critical situations. The system’s design includes a dual-mode biometric authentication process, where users are first identified by their fingerprint, followed by facial recognition to verify identity before access is granted. The implementation includes two subsystems: the first is composed of an Arduino board connected to a fingerprint sensor and a servomotor, which conditions the operation of the second subsystem. The second subsystem is based on a Raspberry Pi as the central processing unit, along with a camera and a solenoid lock mechanism. This biometric approach ensures secure, traceable, and efficient medication management, meeting both safety and legal requirements while optimizing the storage and distribution processes of controlled substances.