Primary care is considered an essential service within the public healthcare system because it is responsible for offering continuity of care, patient-centeredness, coordination of care, prevention, health promotion, and patient autonomy. ** Clinicians are increasingly interested in utilizing clinical pathways to improve primary care quality and service delivery, providing more efficient use of available resources. ** At the secondary care level, clinical pathways are regularly used to ensure adequate management of care for a specific population to receive appropriate and timely care in an institution. It would be interesting to know if this process could have the same benefits within primary care. This literature review aims to screen the scientific literature on whether there have been studies able to address the application of clinical pathways in primary care. After screening both titles and abstracts, 26 papers were selected among 5,807 articles found. After the application of inclusion criteria for this literature review, 10 articles were selected. The results indicate the benefits and the limitation of using clinical pathways. However, the lack of resources in primary care and the resistance to change may limit the adoption of CPs.