Laser-assisted in situ keratomileusis (LASIK) has become one of the most popular options for the correction of low to moderate myopia worldwide. However, complications including optic neuropathy, undercorrections and overcorrections, flap displacement, epithelial ingrowth, flap melting, keratitis, retinal tears, retinal detachments, retinal phlebitis, corneo-scleral perforations, retinal hemorrhages, macular hemorrhages, macular holes, serous macular detachments, choroidal neovascular membranes, reactivation of ocular toxoplasmosis, and irregular astigmatism have been reported. Serious complications after LASIK are infrequent. It is very important to inform patients that LASIK only corrects the refractive aspect of myopia. Vitreoretinal complications in these eyes will occur and only careful and large prospective studies in patients can determine if the procedure exacerbates myopic pathology. Such studies will need to be performed using careful prospective examinations including determination of risk factors, echography of the vitreous, indirect ophthalmoscopy and scleral depression, and possible photography and angiography of the macula region to determine whether the LASIK procedure itself can exacerbate pathologic changes in the myopic eye. In addition, our latest study shows that results may be not as good as expected after RRD surgery. Despite high anatomical success with one surgery, reasons for poor VA include the development of epiretinal membrane, proliferative vitreo-retinopathy, myopic maculopathy, and optic atrophy. Final VA may be limited by myopic degeneration, amblyopia, or delayed referral to a vitreo-retinal specialist.