Carbon-based nanocomposites are emerging as pivotal materials in the development of next-generation wearable electronics, offering an unparalleled combination of flexibility, conductivity, and mechanical strength. This chapter explores the different types of sensors used in medical diagnosis fabricated from carbon-based nanocomposites. Their unique properties such as thermal conductivity, optoelectronic, mechanical, and light weight make them ideal candidate for wearable technologies. Additionally, their biocompatibility and environmental friendly response enhances their potential for health using smart devices.