The persistent degradation of structures due to various hazards is an undeniable challenge. These hazards are broadly categorized into natural ones, such as earthquakes, floods, and strong winds, and those caused by human activities, including ship collisions, excessive traffic, and terrorist attacks. While traditional solutions have focused on structural design and safety standards, there is a growing need to explore innovative materials that offer higher performance than conventional options like reinforced concrete and steel. One promising area of research is the application of new high-performance materials, such as carbon nanotube-reinforced polymer (CNT/polymer) bearings. This study used ABAQUS simulations to assess these bearings as components in seismic isolation systems for bridges, specifically at the junction between the bridge’s superstructure and substructure. The findings revealed that using CNT/polymer bearings significantly extended the bridge's period of oscillation and markedly reduced the bending moment at the base of the bridge piers throughout the time-history analysis. This contrasted sharply with the results observed in cases of direct contact between the bridge’s superstructure and its substructure. In essence, the research underscores the potential for advanced materials in enhancing the earthquake resistance of structures, particularly in seismic isolation applications for bridges.