Dipole antennas play a foundational role in medical telemetry systems, operating across a broad frequency spectrum from MHz to GHz. This chapter delves into the fundamental radiation mechanisms of dipole antennas, detailing how their length, resonant frequency, and radiation efficiency influence performance in biomedical applications. It discusses the advantages of dipole antennas, including their simple structure and effective omnidirectional radiation, while also addressing limitations such as size constraints, frequency-dependent performance, and susceptibility to interference. Special emphasis is placed on the integration of dipole antennas in implantable medical devices, highlighting challenges related to miniaturization, biocompatibility, and signal distortion due to blockage, diffraction, scattering, and reflection within the body. The chapter examines frequency band selection for medical telemetry applications, taking into account regulatory restrictions and the benefits of broadband dipole designs for robust communication. Design considerations for wearable health monitoring systems are explored, along with dipole antennas’ role in in-body communication for advanced medical implants. The potential of dipole arrays for directional telemetry is discussed, with applications in remote patient monitoring and wireless medical imaging. Techni5ques for enhancing the signal-to-noise ratio are introduced to support reliable data transmission. Finally, the chapter concludes with current open research challenges and future directions for improving dipole antenna performance in complex biomedical environments.