Loss of an eye to tumor, trauma, or end-stage ocular disease may be devastating. There is a loss of binocular vision, reduced peripheral visual field, and loss of depth perception. Job limitations may arise, and affected individuals may experience a sense of facial disfigurement. Because eye contact is such an essential part of human interaction, it is extremely important for the anophthalmic patient to maintain a natural appearing prosthetic eye. In the past three decades, there have been numerous developments and refinements in anophthalmic socket surgery with respect to implant material and design, implant wrapping, implant-prosthesis coupling, and socket volume considerations. It has become increasingly possible to provide most anophthalmic patients with an artificial eye that looks and moves quite naturally and in some cases almost as normally as the unaffected contralateral eye.