Changing faculty positions can afford new career opportunities, but transitions should be planned and implemented carefully to ensure that the best choices are made. If you are contemplating a move, you should thoroughly assess all the available options even if you have received an outstanding offer from another institution. Objectively weighing the short- and long-term risks and benefits of all options is often difficult to achieve when choices have strong subjective and emotional pulls and pushes. Upon learning of an impending transition, your institution may make a retention offer, which should be evaluated carefully. When considering a change of institutions, you should seek advice from mentors, trusted advisors, and professional search firm consultants as appropriate. Remember that changing positions will have a significant impact on your family and friends whom you should include in your decision-making process as early as appropriate. You should be transparent with all institutions about your intentions; this will help ensure good future interactions and enhance your reputation for honesty. One of the most important aspects of making a transition to a new job is how you communicate the impending and actual change to your current and future departmental and institutional leaders, as well as colleagues and trainees.