Among the most troubling situations you may face as a faculty member is an accusation of wrongdoing. Regardless of whether the accusation is true, it can be harmful to your reputation and your well-being. It also takes considerable time and effort to handle such situations. Fortunately, most academic institutions and academic medical centers/academic health centers (AMCs/AHCs) have formal processes, policies, and offices to deal with these situations. Depending upon the circumstances, you may need legal counsel to help you defend yourself. If the purported wrongdoing occurred as part of your academic employment, legal counsel may be provided by the institution, which does not preclude you from seeking your own personal counsel. It is important that you comply with all investigations into wrongdoing and understand the pertinent institutional policies and procedures. Maintaining appropriate confidentiality is essential, lest your reputation and that of others who may be involved be further damaged.