The human immunodeficiency virus (HIV) can affect many aspects of a person’s health, including hearing and balance. When a patient infected with HIV develops symptoms such as hearing loss, tinnitus, or disequilibrium, it is reasonable to undertake a screening otovestibular workup and, if no other cause is detected, refer a patient to an audiologist (for management of hearing loss and/or tinnitus) or a vestibular physical therapist (for disequilibrium).