This study assesses the use of Eulerian volumetric velocity images of the ventricular blood flow for estimating material properties of a physiological fully-dimensional FSI model of the systolic phase of the heart contraction. An efficient partitioned, semi-implicit FSI algorithm is employed, coupling a fluid fractional step scheme with a hyperelastic solid model. Cardiac mechanics model parameters characterizing the active contraction and epicardial wall boundary conditions, accounting for the external tissue support, namely the myocardial tissue contractility and the epicardial stiffness, are estimated from synthetic (i) solid measurements only, (ii) fluid measurements only and (iii) combined fluid and solid measurements. The parameters are estimated efficiently using a reduced-order unscented Kalman filter. Ground truth values of the estimated parameters are accurately recovered if the data provides a sufficient temporal resolution. While the contractility estimation only benefits by aggregating fluid measurements to the solid data by a reduced sensitivity to measurement noise, the epicardial stiffness is resolved more accurately when using fluid measurements instead of solid measurements.

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Parameter Estimation in Cardiac Fluid–Structure Interaction from Fluid and Solid Measurements

  • Reidmen Aróstica,
  • Cristóbal Bertoglio,
  • David Nolte

摘要

This study assesses the use of Eulerian volumetric velocity images of the ventricular blood flow for estimating material properties of a physiological fully-dimensional FSI model of the systolic phase of the heart contraction. An efficient partitioned, semi-implicit FSI algorithm is employed, coupling a fluid fractional step scheme with a hyperelastic solid model. Cardiac mechanics model parameters characterizing the active contraction and epicardial wall boundary conditions, accounting for the external tissue support, namely the myocardial tissue contractility and the epicardial stiffness, are estimated from synthetic (i) solid measurements only, (ii) fluid measurements only and (iii) combined fluid and solid measurements. The parameters are estimated efficiently using a reduced-order unscented Kalman filter. Ground truth values of the estimated parameters are accurately recovered if the data provides a sufficient temporal resolution. While the contractility estimation only benefits by aggregating fluid measurements to the solid data by a reduced sensitivity to measurement noise, the epicardial stiffness is resolved more accurately when using fluid measurements instead of solid measurements.