This chapter offers a comprehensive examination of how deneocoloniality can influence the socioeconomic and political future of Africa. The chapter delves into the manifestations of deneocoloniality, analyzing beyond decolonialism postulates to explore delicate forms of socioeconomic and political machinations. It argues that while decoloniality, on the one hand, was a form of struggle against overt colonial control, deneocoloniality, on the other hand, fights covert forms of neo-imperial hegemony enmeshed in the global system. Inspired by the methodological approach to African intellectualism, this chapter analyzes different forms of deneocoloniality and offers pragmatic solutions to African neocolonial challenges. It starts by investigating the manifestations of socioeconomic and political neocolonial challenges in Africa to establish a ground for offering deneocolonial solutions grounded in African realities. It then argues that deneocolonial solutions need to start by changing the African mindset in order to foster African-based ideologies such as vanhucracy, Pan-Africanism and Ubuntu that can promote unity and indigenous development. Next, it addresses the notion that by strengthening regional and continental integration, common continental problems can be tackled jointly. Finally, it argues that African leaders need to redesign the African Monetary Fund and the African Continental Free Trade Area in a way that neo-imperial hegemony is checked in order to establish independence, self-reliance, and the generation of the financial capacity needed for African solutions. With these deneocolonial mechanisms in place, the socioeconomic and political future of Africa will be bright.