This paper examines the integration of Eye-tracking technology with educational games in special education contexts, focusing on assessment and intervention applications. Through a literature review of recent research and implementations, the study analyzes how Eye-tracking technology enhances learning experiences and provides new forms of interaction for students with diverse needs. The research methodology involved analyzing papers from academic databases, categorizing them into five key themes: Eye-tracking as a tool to improve learning and training, Eye-tracking to improve diagnosis and medical training, Eye-tracking as a tool for diagnosing and studying clinical conditions, Eye-tracking in clinical and educational contexts related to autism spectrum disorders, Eye-tracking as a technology to develop or evaluate digital tools and interfaces. Results demonstrate that Eye-tracking technology has shown significant promise across multiple applications, from improving reading capabilities in dyslexia to enhancing emotional regulation in autism spectrum disorders. This technology enables precise measurement of visual attention and cognitive processing, while providing new interaction possibilities for students with physical limitations. Key findings highlight the importance of customization and adaptation to individual learner needs, the necessity of robust theoretical frameworks linking visual patterns to cognitive development, and critical ethical considerations in data collection and privacy protection. Future research directions include developing more affordable hardware solutions, integrating artificial intelligence for real-time adaptation, and creating sophisticated assessment tools. The paper concludes that successful implementation requires careful attention to both technical and pedagogical frameworks, while maintaining focus on ethical considerations. These developments contribute to creating more inclusive educational environments and making quality education accessible to all students regardless of their specific challenges or abilities.