Public interest in personalised nutrition and microbiome science has emerged in recent years, driven by advances in genomics, microbial research, and digital health tools. While these fields hold great potential for improving health outcomes, they remain scientifically evolving and prone to misinformation. Communicating these topics effectively is essential to bridging the gap between research and public understanding, ensuring that individuals receive accurate, evidence-based information to make informed dietary choices. This chapter explores public awareness and misinformation surrounding the microbiome, presenting strategies for effective scientific communication and engagement. It highlights the role of food information initiatives, media campaigns, and interdisciplinary collaboration in promoting microbiome literacy. Additionally, it examines how healthcare professionals and researchers can be empowered to translate microbiome science into accessible guidance while managing public expectations. By addressing communication challenges, misinformation risks, and opportunities for engagement or collaborations, this chapter underscores the importance of transparent, evidence-based messaging in fostering a well-informed public capable of making sustainable, health-conscious decisions.