This work presents a novel hydrothermal method for the preparation of Pt-doped SnO2 on ITO substrates using a non-aqueous solvent based on ethylene glycol. The successful synthesis of Pt-doped SnO2 was verified by characterization techniques such as scanning electron microscope, energy-dispersive X-ray spectroscopy, and elemental mapping. The crystal structure of the synthesized material was characterized by the X-ray diffraction method. The results have shown high purity and uniform distribution of Pt-doped SnO2 particles obtained from ethylene glycol-assisted hydrothermal method. Moreover, linear sweep voltammetry indicated that Pt-doped SnO2 presented strong electrocatalytic activity and good stability for both hydrogen evolution reaction and oxygen evolution reaction in an alkaline medium. These findings suggest that the proposed hydrothermal synthesis is promising for the preparation of metal/oxide semiconductors such as Pt-doped SnO2 nanoparticles, which could be potential electrocatalysts in applications of sustainable developments such as electrolyzes for water splitting and fuel cells.