Using models to interpret data is a fundamental aspect of data analysis, enabling us to understand patterns, make predictions, and derive insights from raw information. In particular, using models transform raw or otherwise mute data into valuable knowledge. In this work we show how an intuition concerning Random Boolean Networks (RBNs) - a well-known model in the field of complex systems - allows the introduction of a new type of observable, useful for the analysis of real biological data. We then apply this idea to single-cell data on humans and mice.

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Using Pseudo-attractors of Genetic Regulatory Networks to Analyze Biological Data

  • Gianluca D’Addese,
  • Carlo Crovetti,
  • Roberto Serra,
  • Marco Villani

摘要

Using models to interpret data is a fundamental aspect of data analysis, enabling us to understand patterns, make predictions, and derive insights from raw information. In particular, using models transform raw or otherwise mute data into valuable knowledge. In this work we show how an intuition concerning Random Boolean Networks (RBNs) - a well-known model in the field of complex systems - allows the introduction of a new type of observable, useful for the analysis of real biological data. We then apply this idea to single-cell data on humans and mice.