This study explores the psychographic factors that affects the prescription decision of Healthcare (HCPs), a valued characteristic of the therapeutic process. This paper focuses on the prescription behaviour which is a function of several factors that dictate the course of treatment by doctors, and the compliance level from the patients. To identify values, attitudes, decision making patterns, and lifestyle preferences of 500 doctors and HCPs that drive medical decisions. Across the study, the data show that improved and more detailed psychographic segmentation can bring clearer and more relevant messaging and, consequently, better outcomes in terms of HCP engagement. The study also discusses novel ethical issues that come with this approach that the author adequately navigates to avoid compromising professional ethic or patients. In doing so, this research seeks to help pharmaceutical companies achieve more precise promotional communication strategies more in-line with the psychographic characteristics of the healthcare professionals involved, and thus foster the development of material that caters both to their career goals as healthcare professionals besides fulfilling their personal potential as individuals. Such an approach may enhance the flow of information, enhance engagements between pharmaceutical organisms and HCPs and ultimately generate a form of patient-centric medicine prescription. The findings of this study help to fill a gap in synthesizing future changes in healthcare communication with applicable practical applications by providing a precise framework for the pharmaceutical companies to take on social media engagement whilst being ethical about it.