Molecular Allergology and Component Resolved Diagnosis
摘要
“Molecular Allergology and Component Resolved Diagnosis” by Michael Benninger, MD and Gary Falcetano, PA-C. Benninger and Falcetano offer an updated summary of the evolution of diagnostic allergy testing from extracts to molecules. As we continue to strive for increased personalization in medicine, the authors offer a comprehensive exploration of molecular allergy diagnostics and the analytical and clinical benefits provided by the assessment of individual allergen components. Benninger and Falcetano focus on three major areas of molecular allergy diagnosis; food allergy (particularly peanut and tree nut), pet allergy, and pollen allergy. The authors explain how through the identification of primary and cross-reactive molecules clinicians can be more precise in their diagnosis, leading to improved risk assessment and more patient-specific exposure reduction and immunotherapy interventions. “Molecular Allergology and Component Resolved Diagnosis” concludes with a look to the future and how early assessment of molecular allergen components may revolutionize the diagnostic approach to allergic disease.