Soil salinity is a major environmental issue that impacts agriculture globally. One of the largest exchangeable sodium salt concentrations in the root zone is seen in salinized soils. The symbiotic relationship between plant species and actinobacterial species that fix nitrogen was a major focus of the current investigation. Actinobacteria species were recognized for their capacity to generate secondary metabolites, which could find use in bioremediation and in promoting plant development. Actinobacteria are found in large quantities in nature, primarily on land and in water. Because of their ubiquity in soil and the rhizosphere, their ability to colonize plant surfaces and roots, and their aptitude to create a variety of secondary metabolites, they are well-known for promoting plant growth. Actinobacteria may withstand abiotic stress through a variety of mechanisms, such as the synthesis of osmolytes, plant hormones, as well as certain enzymes that improve nutrient availability and preserve osmotic balance. Members of the actinobacteria are the most likely candidates to serve as microbial inoculants. In this work, actinobacteria were isolated through the use of selective medium from high salinity soil samples, and their morphological and biochemical properties were investigated. Since actinobacteria improves the plants’ ability to survive high salt circumstances and promotes their growth, this study looked at how effective they are in enhancing plant growth under 0.5 and 1.5% NaCl environments. Actinobacterial diversity in different plant regions, the effect of abiotic stress on actinobacterial diversity linked with plants, and actinobacteria-mediated stress mitigation systems are the main topics of this study. The paper also addresses how multi-omics methods can be used to increase the interactions between plants and actinobacteria, which help plants overcome abiotic stresses.