Because of their wide range of potential uses, nanoparticles of doped and undoped ZnS have attracted a lot of interest. The production methods and many uses of doped and undoped ZnS nanoparticles are examined in this critical study. This review takes a close look at the chemical, physical, and biological synthesis methods, comparing and contrasting them to show their strengths, weaknesses, and new developments. This study provides a comprehensive analysis of how dopants affect the optical, electrical, structural, and functional characteristics of ZnS nanoparticles in various contexts. In addition, the paper evaluates the potential uses of these nanoparticles in many fields such as sensing, photocatalysis, optoelectronics, biomedicine, and more. It explores the effectiveness of doped and undoped ZnS nanoparticles in different contexts, highlighting their unique contributions and possible future research paths.