The presence of pharmaceuticals in wastewater is a wide potential factor that affects the human health as well as environment. Pharmaceutical drugs which are used in hospitals, medical stores, they were using the most traumatic dose and different types of drugs which can be found in wastewater through drainages that can be transfer to the many other water supply areas. The wide range of drugs that can be detected from the waste water are from which including pharmaceuticals, illicit drugs, personal care substances. The source of drugs in waste water Includes it can be from human excretion, agricultural runoff, pharmaceutical waste. It is possible for medications to cause endocrine disruption, bioaccumulation, biomagnification, and antibiotic -resistant bacteria in aquatic creatures when they wind up in wastewater. These hazardous drugs once they entered in to the flowing water, they can be transported in to the surface water, groundwater, and soil. This treatment of wastewater is done using basic technologies like physical, biological and chemical methods. This review paper discusses about the potential risk of waste water in environment and the different hospital plants that treat wastewater that are employed in the disposal and treatment of the pharmaceutical containing wastewater.