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Zinc oxide (ZnO) nanoparticles, for example, have shown great promise as a result of their distinct physicochemical characteristics and strong antibacterial activity. In this work, we used a green synthesis technique to create ZnO nanoparticles from the aqueous extract of Azadirachta indica or neem. The structural, morphological, and optical characteristics of the produced nanoparticles were assessed by means of X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and UV-visible spectroscopy. Additionally, the ZnO nanoparticles’ antibacterial activity was assessed against a panel of therapeutically relevant pathogens, such as fungus and bacteria. The use of Azadirachta indica extract in the green synthesis of ZnO nanoparticles produced well-defined, crystalline nanoparticles. The homogeneous size distribution of the nanoparticles was revealed by TEM examination. The existence of functional groups connected to the extract on the surface of the nanoparticle was verified by FTIR analysis. UV-visible spectroscopy revealed the nanoparticles’ bandgap energy and absorption properties. Enhancing the antibacterial activity of ZnO nanoparticles with the use of Azadirachta indica extract is a sustainable and environmentally friendly method.

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Evaluation of Azadirachta Indica Extract as a Reducing and Stabilizing Agent for ZnO Nanoparticles

  • 会议论文

  • 发表日期：

    2025年

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  • Malik Ifra Nabi,
  • Sabreena Zahoor,
  • Ruhani Sharma,
  • Sunil Chhimpa,
  • Harsh Pandey,
  • Anjali Awasthi,
  • Farah Syed,
  • Garima Awasthi,
  • Hemant Pareek,
  • Kumud Kant Awasthi

摘要

Zinc oxide (ZnO) nanoparticles, for example, have shown great promise as a result of their distinct physicochemical characteristics and strong antibacterial activity. In this work, we used a green synthesis technique to create ZnO nanoparticles from the aqueous extract of Azadirachta indica or neem. The structural, morphological, and optical characteristics of the produced nanoparticles were assessed by means of X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and UV-visible spectroscopy. Additionally, the ZnO nanoparticles’ antibacterial activity was assessed against a panel of therapeutically relevant pathogens, such as fungus and bacteria. The use of Azadirachta indica extract in the green synthesis of ZnO nanoparticles produced well-defined, crystalline nanoparticles. The homogeneous size distribution of the nanoparticles was revealed by TEM examination. The existence of functional groups connected to the extract on the surface of the nanoparticle was verified by FTIR analysis. UV-visible spectroscopy revealed the nanoparticles’ bandgap energy and absorption properties. Enhancing the antibacterial activity of ZnO nanoparticles with the use of Azadirachta indica extract is a sustainable and environmentally friendly method.