As a key component of teaching space in primary and secondary schools, the rationality of campus furniture design is directly related to the physical and mental health development of students. This paper focuses on the application of Human-computer Interaction (HCI) concept in primary and secondary school campus furniture design, aiming at promoting students’ physical and mental health development through technological innovation. Through literature review and current situation analysis, this paper reveals the universal problem of current campus furniture design. Based on the concept of human-computer interaction, this paper puts forward two innovative design strategies: strengthening posture correction and health monitoring, promoting function optimization and module integration, and completes relevant design practice. This study provides a new perspective for campus furniture design, emphasizes the design concept of taking students’ physical and mental health development as the core, and aims to provide reference for research and practice in related fields.