This study focuses on the enhancing effect of personalized design of museum digital humans on users’ emotional experience. In the current era of rapid technological development, the digital transformation of museums is accelerating, and digital humans have emerged as a new medium for display and interaction. However, the current design of museum digital humans mostly emphasizes functional realization, with insufficient consideration given to users’ emotional experience. This study conducts research on personalized design in dimensions such as the image shaping, language expression, and interaction mode of digital humans, aiming to fill this gap and effectively enhance users’ emotional experience, making museum digital humans into emotionally appealing cultural communication carriers and strengthening the cultural communication effectiveness of museums.