This chapter focuses on the transformation and future orientation of social sciences and universities in response to contemporary global challenges. It critiques the traditional disciplinary divisions within academia, advocating for a more integrated and interdisciplinary approach to understanding and solving complex societal issues. The analysis emphasizes the role of social sciences in bridging the gap between the natural sciences and humanities, suggesting that this convergence is crucial for addressing the multifaceted crises of the twenty-first century. The author proposes the concept of the “Future University,” a novel institutional model that is adaptive, interdisciplinary, and capable of producing knowledge, directly relevant to society’s evolving needs. Building on Wallerstein’s examination of the global economic system and its impact on social sciences, the author argues that the World-Systems Theory provides a framework for understanding the historical and contemporary dynamics of global capitalism, influencing this chapter’s critique of traditional academic disciplines. Wallerstein’s ideas inspire the main argument for a more interconnected, interdisciplinary approach to social sciences, reflecting on the necessity for academia to adapt to the complexities of the modern world and contribute effectively to addressing global challenges. This university model is envisioned to be more responsive to technological advancements, societal shifts, and the global knowledge economy, ultimately contributing to a more equitable and sustainable future.