This study presents the response of the atmosphere and ionosphere to the precipitation of energetic electrons from the Earth’s outer radiation belt into the atmosphere during a weak magnetic storm on February 1–4, 2015. Information on the spectra of precipitating energetic electrons was obtained from experimental data from the polar satellite Meteor-M2 using integral electron channels with energies >100 keV, >300 keV and >2 MeV. To recover atmospheric response we use one-dimensional radiative-convective model with interactive neutral and ionic chemistry. It is shown that the strongest response in variations of ionization rates, ozone, as well as ozone-depleting atmospheric components occurs during the main phase of the storm and at the beginning of the recovery phase, when the most intense precipitation occurs during substorm activity. It has been established that mesospheric ozone loss up to 24% is accompanied by an increase of HOx and NOy families during the main phase and at the beginning of the recovery phase of the storm on February 1–4, 2015.